P

Primekg MCP

A project to import the Precision Medicine Knowledge Graph (PrimeKG) into the Neo4j database for biomedical data analysis and exploration.
2 points
24

What is PrimeKG to Neo4j?

This is a project to import the Precision Medicine Knowledge Graph (PrimeKG) data into the Neo4j graph database. PrimeKG integrates 20 high-quality biomedical resources, describing 17,080 diseases and more than 4 million relationships.

How to use PrimeKG to Neo4j?

The project provides a complete processing workflow: 1) Download and process PrimeKG data. 2) Import it into the Neo4j database. 3) Provide query and analysis tools.

Use cases

Suitable for biomedical researchers, drug developers, and data scientists to conduct disease association analysis, drug discovery, and precision medicine research.

Main features

Multi-source data integrationIntegrate 20 high-quality biomedical resources to achieve cross-resource data association.
Graphical displayProvide an intuitive graphical interface through Neo4j to display the complex relationships between entities such as diseases, genes, and drugs.
Flexible query and analysisSupport the Cypher query language and perform complex relationship path analysis and pattern matching.

Advantages and limitations

Advantages
Integrate multiple authoritative biomedical databases with high data quality.
The graph database structure is suitable for displaying complex biological network relationships.
Provide a standardized data import process and query interface.
Limitations
Basic knowledge of Neo4j and Cypher is required to make full use of it.
The data volume is large, requiring sufficient storage and computing resources.
Regular updates require re - importing the complete data set.

How to use

Prepare the environment
Install Docker and the Neo4j database (version 4.4 or higher is recommended).
Download PrimeKG data
Download the latest PrimeKG data set from the project website.
Data preprocessing
Run the preprocessing script to prepare the data for import.
Import into Neo4j
Use the provided import tool to import the processed data into Neo4j.

Usage examples

Disease - drug association analysisExplore all drugs related to a specific disease and their mechanisms of action.
Multi - hop relationship path discoveryDiscover the potential associations between diseases through intermediate entities such as genes and pathways.

Frequently Asked Questions

How much storage space is required to store PrimeKG data?
What is the data update frequency?
Can I use this project without Neo4j experience?

Related resources

PrimeKG official website
The official website of the PrimeKG project, including data download and documentation.
Neo4j Learning Center
Official Neo4j learning resources, including Cypher language tutorials.
Project GitHub repository
The source code and issue tracking of this project.
Installation
Copy the following command to your Client for configuration
Note: Your key is sensitive information, do not share it with anyone.
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